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Home > Types of mesothelioma > Biphasic mesothelioma

Biphasic mesothelioma

Biphasic mesothelioma is the second most common type of mesothelioma cancer cell.

In order to diagnose a case of biphasic mesothelioma, a biopsy is required. A type of diagnostic surgery, a biopsy involves the removal of a section of suspect tissue for examination by a histopathologist.

Biphasic mesothelioma was once perceived to be a lot less common than it has recently been found to be. Initially viewed to occur in approximately 25% of all mesothelioma cases, biphasic mesothelioma occurrences have recently jumped by an estimated range of 20 to 38%. How can such a significant rise be explained? Many experts believe it is down to the biphasic cellular pattern.

Biphasic mesothelioma, or mixed mesothelioma, contains a mixture of epithelioid and sarcomatoid cells. The cells can present themselves in the form of a true mixture whereby sarcomatoid and epithelioid cells are intermixed amongst one another; or, the cells can present themselves in the form of an isolated mixture whereby sarcomatoid and epithelioid cells are separated from one another throughout different regions of the tumor.

The treatment options available for biphasic mesothelioma are the same as those used to combat epithelioid and sarcomatoid mesothelioma. Of the three histological categories, biphasic mesothelioma has the shortest mean survival time at six months; because of this, biphasic mesothelioma sufferers might elect to choose a more experimental or radical treatment option.

Unlike sarcomatoid and epithelioid mesothelioma, biphasic mesothelioma does not have a unique cellular pattern unto itself; rather, biphasic mesothelioma consists of a mixture of epithelioid and sarcomatoid mesothelioma cells.

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